Tuesday, January 22, 2013

What Is Botox, (Botulinum Toxin Type A)?

Botox (botulinum toxin type A) is a synthetic form of toxin or the biological toxin produced by the bacterium Clostridium botulinum. It's the same toxin that causes a life-threatening type of food poisoning called botulism. If one consumes the toxin, orally, in sufficiant ammounts, the toxin blocks nerve signals from a persons brin to the muscles, paralyzing the person. Immediate medical care must be sought if botulism poisoning is suspected.

Alan Scott, MD, a San Francisco ophthalmologist, and Edward Schantz were the first to work on a standardized botulinum toxin preparation for therapeutic purposes. The same toxin, in very small amounts are used by doctors to treat health and cosmetic problems, including;

Temporary removal of facial wrinkles
Severe underarm sweating
Cervical dystonia - a neurological disorder that causes severe neck and shoulder muscle contractions
Blepharospasm - uncontrollable blinking
Strabismus - misaligned eyes or lazy eyes
Overactive Bladder Treatment

There are more than 119 clinical research involved in treating various other conditions with Botox.
Botox injections work by weakening or paralyzing certain muscles or by blocking certain nerves. The effects last about three to four months. Side effects can include pain at the injection site, flu-like symptoms, headache and upset stomach. Injections in the face may also cause temporary drooping eyelids. You should not use Botox if you are pregnant or breast feeding.

According to FDA, there are three botulinum toxin product in this class,
OnabotulinumtoxinA (marketed as Botox/Botox Cosmetic),
AbobotulinumtoxinA (marketed as Dysport)
RimabotulinumtoxinB (marketed as Myobloc)

Information for Healthcare Professionals by FDA

For more Journal Articles.

MYOBLOC® is a registered trademark of Solstice Neurosciences, Inc.
Botox® marks owned by Allergan, Inc.
Dysport™ is manufactured by Ipsen Biopharm Ltd.